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[42]]Liinddee ee l. aaccuu ann aaggessuu oonceettatioons nn aaffccivve iiorrerr:: DDfferenncceebbtteennplasmm and seerum nnrrlltton o ymppooss..AAttaaPPycchiaarrSScaadd 80::22-377 999 [44]] Fraazzrr AA eettall lassaaann ryttrrcyyte llccrrolytes ii ffectiivv diiorreess J ffect Diissrd ((22::00--33 9983. [44] jjruu N. lleeccttrrlyytes nnbbllooood nnennogennuu ddeprrssion. cctt PsyychhiittrrSSanndd 88:599--88,,1172. [[55] Cade FFA. signifficantt elevaation ffppllssaammgnesium eeeess in cchiizoophhrenia nnddddeerressivv ttatts MMddJJAAss ::99--, 9964 ((466) uurr KW. aanneesium foo eerroprotectiinn niisshheemicc ttrokkee rrttoonnaale oo use nn vvddncee ffeefeccttivenesss NN ruggs. 001; 11::9919330. ((77)) (48)Thorax. 9972 aach; 27(2): 112211..MMggesium nn pttiienns nndeegging open-heart surrgerry ..PP..HHoldeen, .. .. ooneesscu,, nnd .. .. ooleer ((44)) DDpprrmmnntt offCCrdiioohooracic uurgeery aadd Crriioooogg,,GGnnooffeeHHospptal,, Copenhaaggn Denmark OOI: 0.310099/1401743778099003355 50) peziale , uuvvlo ,, Fattooc , ttal. Arrryythmia rroohyyaaii aafter oronary rtery yyppss graffttiing: eeiimmnnssooffmmggeeiummssllffttee aaddiinnssttaationn Thorrac Cardioovvasc uurg 000; 88 226.[Medlinee (51) ooiiii H,,WWllner ,, arhhofer ,, Andell ,, rruuf ,, MMaaeerr . MMagnesiumm uullffaatte educess nnrra--and ppootoopeeaaiieeaaalgesi eeuurrmmnntt. nnstt AAnalgg1998; 7: 00660 ((22CChhnnee oo blooo anesiumm oonncennttrraattoo inpptienntt nneeggiinnggssuurriiaa yyccrriiaa eevvssccularriizzttion. aasternak, tt a;;MMgneess Ress. 0000 Juunn19((2):1107--12jj; ==ppubbmed&ccmd=Retriivv&&ddopt==abbssttaaccttplus&&liist__uuidds=1699557722 ((33 Dormann BH,, aaddee MM uureette SS ttaal. aagnesium uupplemmeetation n thh prrevention of rrhhttmmiiaa in eeiitticc aaiients nneegoiing suurrgrr oorr coogeenniittaall eerr efects. m eart 2000; 33::522288[[MMddiiee (54) nn Torrac Suurr 2001;722:1255-112262 55))DDlluummau ,, rraanrryy JJCC,, otttiineaa , uuowski GG oorrbauu JJ,, Moreau . Cooparattveevvssular ffeett of magneeiim uulpphatee nnd icardippnee uriinn ardiopuummnnaayy byppss FFeecc)). nn Fr AnesshhRRaaimm119999; 44 4953.[[eeliie]] (56) Perioperaaiiee coronnryy rttery ppsm nnooffppuupp coronnaarr rreerr byypasss rrffiigg nnd tt possiblee eellation iihhpprroppeeattiie yyoomagneeeemii.. Ann hhrrac aaddovaasc urg. 0000 FFeb;122(11::2266 PPII::1157220772 PPbbee iidexed oorr MMDDLINE] uubbeed ((55)) Joorrnal nnernationl Journaa f eeatollooggy. SSNN 9925-57710 Issue oolumee 77 NNmmeer 4 MMy, 00003 (588) oommnn B,,SSde MM Burreette SS, tt al.. Magnesiummsupplementattoo nn the reventioonn of rrhythhiissinn eeiatric aaients nnerroing uurrgeryy ffr onggnntal eertt eeffectt. Am eert 000; 339: 2288[[edlineeLamp of Lff II yo uuffrrwwtt hhooniicc eeltt rrbbees, lacc f energy, oorrcircuuation, digestiivvee probleess iigrainss ccrrmpssaaddggnnrrllbbddyy ainss oou maayybbeedefiiiinn ii aavvrr important ee nneerrestimaaeeddmmnnral. ewwr why ee hw ssential aanesiium ss t aantaaininng vrrlll haallth aadd treating chrrnnccdiisseasss. hhee youucconnsiderr allthe eelllaa rocessess hhii miineerrl ss involveddii,,aad oow liikkll ou reett eedeficienntt,,ii sseeaass tt nnderstanndd many eople rr eddeesly uuffrrnn witt eess than ppiiaa entaall nn pyyiial eelleenn.. WWyy rr eess eeiciieenn?? II the ooddold aas,,therr waas plenty ff aannssuu nnouu atter nn oollss tt wwsseessy oottke nnenoouuhhttrruuhh teediett. ooeeerr,,ttee mnnrrllccnteenn ff orr siiss haa eennssvvrrly eellttee and eennwwddiik ottlldd oo soffttnneeddwttee. nn addiittoonntt thhtt,,wwe aat ore rrcceessdd oodd ann ive nnaannaagge hheeeewweeaaeeccoossaattlyyexppoosee oo heavy mmttaas nn oxiis. ven ntense xxercissee high rrttii iitt,, cnntracepttiies,, caaffeeiinnee llccoohhll strress nndd suggar ddeeppeeee levelss fftthhiissccrucciillmmiinnrrll. So whaa dd wwe eeeedd aannesium oorr?? Maagnessuummiissnneeeessarr oor very eelluulaa rrocesss iihhnnoorrbbddessbbcuuee eevveerrthinn equuiirees nerggyy ann theebboodds iigghheeeerryy ccoopoound ((AAPP) uusst e oonndd oo mmgnnessiiuummii oorrer oobb efffcctiiee((11. eeww realizze hhtt ttii beauttffuu iieeaallii esseentiil oo both hh pprooductiioo andd atioon f nnuuii.. eeiiiinnyyiicreases nnssuuii eessstaace aaddtte rriisk off eeeeopinng iabetess((22,,3,,,,). Gluttaathionnee, hhe nnll knnwwnnaatiioxxiiaann tt neutralize eeccrr 66 nn iss essential or eetoxiffccttoo and rrttcciigg orrccllll ffoo cheemiials an heaayymetaass,,rreeqiirree aagnesiuum oor yytthhssiss 7). MMggnnssum ss the llimatt hearr eeiiiiee ttllwers llood rrssurr by ellaxing hhee booddvessee aall nd eeppnn hh lloddttii,,tteaas rrrrgular hhartbeaatss ((rrrryyhmmias) 88,,99,,00111,,1122))aaddccaanneeeenn rreeeettyoo haaiiggoorrddiiggffoo aa haarrttaatttaack 1,14)) I you arr ccnneenndd bbouut tteessrrnntt of oorrbbnnss ttddee have oonn ttaa itt i oo nnrraaee aaccuu iittkeettaa llwwrr tte iikkoo ossteoporosiss 11))bbtt in faatt mggeessiimm tthaa nnrraaeessbbnn iieeaa deennsstt nnthheeeellerly (166.. AAmmggeeiimmddffiicceecc caann lleeddddiieeccttyy tooccaacee bbeeaasse f hh rrll iit llys nn rrooeettnn ttee eerrmeeabiiityyaaddssaaiilltyyooffcceell mmmmrrnnss (1771188,,9922) umeeoouu ttddeess haaee shhoonnaaliink eetweenn maggeeiummlevveessaaddtteeddvvllppeenn off cannee 22,,2222,,44,,5522)) Whheennii ooee ttoommeettaa heeaath,, maannssuu eeuuaaee ttee exxccttbblliiyyoo the enttall neerroossssssee aad sttddeesshhvv ssownnttaa nn asscciittoo bettwwee agnnssuu evell nn AAHH 27,,8,,9933)) ggrrssiinn (11,,2233,,4433)) AAzzeemmrr ddssaass (336)) nniitt ((7733,,9)),,bbppllrrddssrree 44,,11))aaddddppeessiinn (42,,33,,4444)) aannssiiuu ssooeeof tthheeffwwssbsttnnccs hhttccnnccrrss hheebbooodd--bbainn-bbrriiee ((6)) annd ss iiee oossttooeevvcciiss((44))bbccuueerrssaacceessbbelleeeeittssllww hh hhmmccaa roccss ttaa ccusee aassve braii cclllldeathhann leeaasstt perrmmaaeenn diaaiiiiyy OOthooeeii,,aaddmmnnllaaddooee--eerr uuggrr eerreeaaeemmgnnssuu eevvll nntteebbdd (4488,,44,,55,,55,,52,533 nn pooss operaattvv ooppiiattiinn sscc ssaattiillffbbiillttoo,,aattrr ssppssss blooddccoossaaddrhhthmmddssrreess((5544,,5555,,7755))aarr reedduuccdd witt mmggeeiiuummssppllemmnnaaionn.. NNwwIIkkoo whh yoo needdii,,hhwwccnnIIggttmmrr?? AA lrreedd diiccuussddii iss xtreeeeyyhhrr o ee eeoogg maaneessum rrmmtteeddee llnn. oouu caa taaeeorrl uuppllmmnnssbbtthhgg dooee maayy aasse nneestinnaa diissooffrr..TTeeeesseettwwyytt ee yoouu leeeell up o hhrr heyyssooll be,,ii o ppll tttt thh kin. oo onny ooess hss aallww yyouutoo aakk inn ooee buu ssaa dee beeeeii,, ittdduubbes pp ass naattrrllppiin eeiivvrr T ssbbccuueettee pttnn antii-inflammattooyy aaddmmssccee--rrllxxnn rrpprtties offmaggnnesiumm caannbe onccnnttaaed iieecclyyoo aafeecteeddaaeas uuh as iiaabeettii eerrpaahh,,ssortts nnuuiess, arrthhriitis, gout nnddmmsclle chess TTeee rraall is noo eason oo nottssuppplementiingg mmagneeiimm and o ooyythaa cann uucciionnwwtthhuu itt. RRffrenncees:: ()) [[]] PPaolissss G, cceeeenn AA, DOnoofriiooFF, eeeebvvrr P:: aagnneeiimm and llccsee omeossaassiis. iabbtoolloogaa 33::5511111144,, 9990[Meddline] [3] aalleerrJJ,, uchaanan ,, aatarajan ,, Antoniippiilllai , eergaann R, uudd ::MMggnneessum eeicienccy rrduuces nnsslii resiissttance nnddiincreased thrombbxane yynthessii.. Hypprreesion 1110241022, 999933 [4] ooeez-RiidduurraaR, iilleettWWCC iimm EB, ii SS Stampfer JJ,,MMannoo E, Hu B: aagnesium inttaaeeannd iskk of ype diabetes nn men nndd ooee.. Diabeeee aae 77134411400 200044 55 KKoo WH, olssoo RR, iieeo JJ, oo JP, aatson L, rrnccttiiFL::Serum nd iieeaayymmaaggeeiiuu anddtteerisk oor yyee22 ddabetes ellituss: hh Atheroocclleeoossis iikkin oommnniiiies tudyy ArcchhInnterrnnMed 159:21511, 9999 (6) ttpp/// 77)) Virginiia iinniich, M. .. Smith,, M. ..BBraauunner, nnd hhllppWW Majeus.. lluuttttiionne iiooynthesss nnhumaanneeryyttrrocytes. eppartmeett oo Internal eeiccine, aassiiggoo nniiveerriitt SShhoo of eediccinee J lln nneett 119771 March; 003):: 00553. (8) Ottt, eeter nn eesterr, aal. hhooulld magnessium ee aattoo hherroutinee hheerapy oo acute yyocarriial nfarcction?? mmrriiaann HHeerrt oournal, ol. 2244,,NNo. ,, Occtobbr 9922 ppp. 113-18 (9)DDubeey, nnaaii annd oooooon, iihhrr.. Magnesiium, yycaarrdial sscchheei aaddaarrhythmias: hhe ooll oo agnesium nn yyocardialiiffaaction. ruugg,,VVll 37, 9999 ppp. --77.. (10)Ennggaanndd Micchaee RR, ttaa.. Maggneeiiuu administration nnd yyrhhttmmas fter aadiac urrggery. oorrnaa of hhee American eeddiccl ssssociiaaiionn,, Voll. 66, oo 7,,Nooember ,,1199, pp.. 223995-244022 ((1111) uuuu,,SSllmm, ttall nnttavenoouu aaggnessiumm nnaaccte myocaarriaa nnffarrccttiin.. Ciicuuattioo,, Voo.. 77 o. ,, JJnn 19993, pp 20433-46 ((22))WWooods, eennt ..andd lltthhrr Suusan. oonnggterm uttcomee ffeer nnttrrvvnous agnesium uulphatte nnsssseetteed cute myyccrriillinfarctiio:: thee second eeiccessterrInnrravenous agnesiumm nnteerrention rriill(LIMIT--2)..Thhee Lancet, Vol. 43, April ,,119944 pp. 1166-19 ((133)Mannzz,,MM,,eett al. eehandlunn vvon herrzrhyyttmmuussttrrnngen ii mmaannsiiuu.. Deetsschhee eedd occhhnnsshhiftee, oo. 11,, Noo. 0, aarrhh , 990, pp 3866--900 ((4))Iserii, LLlooyy TT,, tt al.. aanneesium hherapyy of ccrriic arrrhhyyhmias nncrriticaal--care eeddccne. aannssiim, ooll.. 88 19889, pp 299-306 (11) 11))SStendig-Linnbbeegg G. eeppeerrR.. eeiichtteerrII..TTaaeeuuaa bbne eesst iin ttoo yeeaar oontrrooled rriaall ffpperooral mmaaggeeiiuu nn osteooporosis. eepprrttmennt ff Physioology nd hhrrmmcclogy, aakllr aauulltt ff Meedicine,, ee Avivv UUniverssiityy Israael.. aanges eess. 1993 uunn;6(22))::1155--66.. 11))AAggiieeii L.J..Magneesiium ooccnnraation aariittiinn ddrrng aacinooeennssss..MMagneesiimmBBll. 99799; ::46--8. ((11)) nnhhiieerrii .J., oolleery, .., oodduu,,PP,, Durlach,, .. EEpprrmmntaallrrlaionships eewwee magnesiimmand aacer.) Maggesiuu Bull. 19911 3::-5 (19))llndellll, .WW.. hh antiicancer ffeecc oo aannssum. eddccllHHppttessiss 980; ::66--7. (220)Durrlaach ,, ara ,,GGiitt--aaaa A, oollrryy PP Reellaattionship eeweennmmaaggeessum,, annccrr aand aaccinoggenic rr anticanccrrmmetals. nniiaaccrr RRss..1186 NNov--ee;;(())1155--11 (211)Alekkaadrrooiizz J., llcharski,,JJ,, zzggooskk,, A.,,Lisieewiizz J. eeukoo--anndd ooccggnesis inn the light ffssuuiissoonn mmttaabooissmm ff maggnesiium n uunnvee nn biiccnnssii..Accaa Md. Poll. 99700 111:289-3002. aassrr lloo 19711; 7724455 ((22))DD.. Dehheinzelin, ... eerr11 ..R. uuccc,,M....SSaallmm11,, VVMM. aa CCuu1,, R.M. lliieeiia,, ....NNssimotooanddC. Hooeezz yypomaggeeeeii ii criitically ll canccee aaiints: pprroossecttive ttdd ffppeeiittv factors.. rrzzJJ MddBiiol Ree,,Deecemberr 00, Volume 33((22)) 4444-1448 (33 mmrican oouurrnnll of ppiieemioooggyy VVool. 63, pp 232-235) ((44 Jouurnnlloo tteeAericcn eeiiccal ssocciation, oo. 99,,pp.. 6688 22))Pauuniier, L.., aaddee,, ICC:: orrmalland bboomal aannsiuummmetabooiissm.. Buulll. ff ooss..ffrrSSiicc Childr..((TTrronto) 9955 114:116-233. (26) AA 99 991, Drr P.. ccrruummffPPiierroonnppreseeteed paper entitled OO tthe aaseOfftteeRRrriityy ff ancerr nn ggpp,,whhich waas rrnntted nntheeBulletin fftteeAAademyyof edicine,,anndd the uuletii oo he FrennchhAAssciationnffr he ttudyyoo aancer nn uully, 1931. ttpp/// (277 uulaacch ..Clliniiccll aspeett ffchhoonic aannssiium defficceennyy,,iinnMM eeeellgg Edd..MMagnessiim nnHHaalth nd iiseaaee NNeww ook, SSectrum uullcctions,118800 ((88..ooziielec ,,SSttrrbbaatt--HHeerreelin ..Asssessmeet f aannsiiummllevells nncciildrennwwitthhaatention eeffcit yypperaccttiiiitty dissorrdeer AAHDD).. Magness Rss 10022))::443388,, 97. (299))KKzielec ,, Staaobrat-HHeemelii . sssseessmmnn f agnesiimmllvvelss nnchiillrrn iithhaattnnttoo deficit hyperracctivvtt iiooddr (AAHDD). aannees ee 10((22):143-88 9997. (30)).SttarroorrattHrmeeii ,, ooiillccT. hh eefects f agneeiummppyysiooogiiaa ssppllmmnnaaiin n yyeeaactivitt ii chiiddee wwth ateetion efiicit hypeeaattvviiyydissorrder AAHD). PPsstive ressonnss oo aanesiuu rrl ooddngg test. aagges eess10(2):119956, 9977 [[11 zznwwasser EE e aall Stimulant-likk eeffeects f maannessumm nnaaggrrssiionn innmmicc.Pharmmaccool ioohem eehhv 55(():11155-9,,11996.. [322 eerrottee GG yyeeAAbbehhvvoo nnddmagnesiummmmtabbliism..MMagnnsium 5:22001-1100 1188. [[33] BBnnettt PP, MccwwnnLM cEwee CC ooee EELL heeSSipplley Prrooeett:: reatiingg ood lleergy oo ppeeent riminaal eehaaviiuur nn commmmuuniiy eettingss. Nutr nniioo ee 88:77788,, 9998. [34] irow GKK, irrch NJ, teadmmn P, aasee G. llsma agnnessuu eeeels nna poppllttiioonn fpsycchhaattii aaiients: oorrlltioonn iihhsympttmmss Neuuropsychhbboollgg 00(2-3):773388 999944. [[5] aattaak MM aaggeeiium deeiiieennyyaallees gggressivv behaavior nn caatecholaamminee fnntioo.. Bhhav euroscci 00(2))3344--11 1988 ((66))nnrrssiiEE, ggz , olnaarr ,, aakooS. issturbannessoo magnessuu oonccnnttraaioossii vvaaiius rain rraassin llzzheemmeer'ss iieasse. .. Ettoo Univversityy, uuddapest,,Hungarry. aanns ee. 000 eep;13 (3)):1889-9966 (377BBiitt RA. nnxiett neurrsii:: Teellccttteeccoonectionn. IIt Clin Nuutr Reevv551144 998855.. ((88SSeeiiggMMSS Bergeer RR SSiihhll .. aaentt ttetany nndd anxieeyy,, mrriiaa Mg eefcciit,, nn oommccllemmia. iis eerv yss 336:4466--55 19955.. (3399Duurlacch ,, Durlaach ,, a ,, tt ll.. Magneeiium nndtteraapeutics. aannee Res ((//4)::113-28,,1994. [40] eergge SS,,Rooeenstein ,,Rubinow RR, tt al. SSFF aagneesiium nn fffctive disorrddr: aakk ff correelaaionn with liiniicall oorrse ffttrreetmenn..PPychiatrry ee 1(():1339-46, 9994. [[41]] iirroovv KK,, iirrcch JJ, Steeaddaan , Rammee RGG llassaa aagneeiium eeeess nn populaatiionnoff pyyhiaatric aattiients:: oorrlations iitt symptoms. Neuroppsschooiilogyy1194;330((--))::3388 1199.. [42]]Liinddee ee l. aaccuu ann aaggessuu oonceettatioons nn aaffccivve iiorrerr:: DDfferenncceebbtteennplasmm and seerum nnrrlltton o ymppooss..AAttaaPPycchiaarrSScaadd 80::22-377 999 [44]] Fraazzrr AA eettall lassaaann ryttrrcyyte llccrrolytes ii ffectiivv diiorreess J ffect Diissrd ((22::00--33 9983. [44] jjruu N. lleeccttrrlyytes nnbbllooood nnennogennuu ddeprrssion. cctt PsyychhiittrrSSanndd 88:599--88,,1172. [[55] Cade FFA. signifficantt elevaation ffppllssaammgnesium eeeess in cchiizoophhrenia nnddddeerressivv ttatts MMddJJAAss ::99--, 9964 ((466) uurr KW. aanneesium foo eerroprotectiinn niisshheemicc ttrokkee rrttoonnaale oo use nn vvddncee ffeefeccttivenesss NN ruggs. 001; 11::9919330. ((77)) (48)Thorax. 9972 aach; 27(2): 112211..MMggesium nn pttiienns nndeegging open-heart surrgerry ..PP..HHoldeen, .. .. ooneesscu,, nnd .. .. ooleer ((44)) DDpprrmmnntt offCCrdiioohooracic uurgeery aadd Crriioooogg,,GGnnooffeeHHospptal,, Copenhaaggn Denmark OOI: 0.310099/1401743778099003355 50) peziale , uuvvlo ,, Fattooc , ttal. Arrryythmia rroohyyaaii aafter oronary rtery yyppss graffttiing: eeiimmnnssooffmmggeeiummssllffttee aaddiinnssttaationn Thorrac Cardioovvasc uurg 000; 88 226.[Medlinee (51) ooiiii H,,WWllner ,, arhhofer ,, Andell ,, rruuf ,, MMaaeerr . MMagnesiumm uullffaatte educess nnrra--and ppootoopeeaaiieeaaalgesi eeuurrmmnntt. nnstt AAnalgg1998; 7: 00660 ((22CChhnnee oo blooo anesiumm oonncennttrraattoo inpptienntt nneeggiinnggssuurriiaa yyccrriiaa eevvssccularriizzttion. aasternak, tt a;;MMgneess Ress. 0000 Juunn19((2):1107--12jj; ==ppubbmed&ccmd=Retriivv&&ddopt==abbssttaaccttplus&&liist__uuidds=1699557722 ((33 Dormann BH,, aaddee MM uureette SS ttaal. aagnesium uupplemmeetation n thh prrevention of rrhhttmmiiaa in eeiitticc aaiients nneegoiing suurrgrr oorr coogeenniittaall eerr efects. m eart 2000; 33::522288[[MMddiiee (54) nn Torrac Suurr 2001;722:1255-112262 55))DDlluummau ,, rraanrryy JJCC,, otttiineaa , uuowski GG oorrbauu JJ,, Moreau . Cooparattveevvssular ffeett of magneeiim uulpphatee nnd icardippnee uriinn ardiopuummnnaayy byppss FFeecc)). nn Fr AnesshhRRaaimm119999; 44 4953.[[eeliie]] (56) Perioperaaiiee coronnryy rttery ppsm nnooffppuupp coronnaarr rreerr byypasss rrffiigg nnd tt possiblee eellation iihhpprroppeeattiie yyoomagneeeemii.. Ann hhrrac aaddovaasc urg. 0000 FFeb;122(11::2266 PPII::1157220772 PPbbee iidexed oorr MMDDLINE] uubbeed ((55)) Joorrnal nnernationl Journaa f eeatollooggy. SSNN 9925-57710 Issue oolumee 77 NNmmeer 4 MMy, 00003 (588) oommnn B,,SSde MM Burreette SS, tt al.. Magnesiummsupplementattoo nn the reventioonn of rrhythhiissinn eeiatric aaients nnerroing uurrgeryy ffr onggnntal eertt eeffectt. Am eert 000; 339: 2288[[edlineeH.I.D. Lights Work Better than Halogen

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